Application Data: Positive Ion Measurement by Triethylamine Removal
Using the desalt tube "Solnac Tube" for LC/MS! TEA was removed online.
When analyzing highly polar acidic compounds using reverse phase partition chromatography, adding basic ionic species to the eluent can enhance retention by forming neutral ion pairs through ionic bonding. Common basic mobile phases used for ion pair formation in LC/MS include triethylamine (TEA) and dibutylamine (DBA). However, when detecting positive ions, it is believed that ionization suppression occurs with almost 100% probability. In this case, nicotinic acid and uracil acid were used as samples, and TEA in the sample solution was removed using a solid-phase extraction tube for positive ion measurement. For details on conditions and analysis results, please download the catalog. 【Infusion Conditions】 ■Samples: (1) Nicotinic acid 10 ppm solution, (2) Uracil acid 10 ppm solution ■Solvent: CH3CN / H2O = 50 / 50 + 0.1% TEA ■Flow rate: 0.1 ml/min *For more details, please refer to the PDF document or feel free to contact us.
- Company：プレッパーズ 本社
- Price：Other
